
Depression: Symptoms, Diagnosis, and Treatment in the UK
Depression, also known as Major Depressive Disorder (MDD), is a common and serious mood disorder that affects how you feel, think, and behave. It is characterised by persistent feelings of sadness, hopelessness, and a loss of interest in activities once enjoyed. Depression can lead to a range of emotional and physical problems, making it difficult to carry out day-to-day tasks and, in severe cases, causing individuals to feel as though life isn’t worth living.
A more chronic form of depression, Persistent Depressive Disorder (Dysthymia), is diagnosed when symptoms last for at least two years in adults or one year in children.
Symptoms of Depression
For a diagnosis of Major Depressive Disorder, five or more of the following symptoms must be present during the same two-week period, with at least one of the symptoms being either depressed mood or loss of interest or pleasure:
Emotional Symptoms:
- Persistent sadness, emptiness, or hopelessness.
- Loss of interest or pleasure in almost all activities.
- Feelings of worthlessness or excessive guilt.
- Recurrent thoughts of death, suicidal ideation, or suicide attempts.
Physical Symptoms:
- Significant weight loss or gain, or changes in appetite.
- Sleep disturbances, such as insomnia or oversleeping.
- Fatigue or loss of energy.
Cognitive Symptoms:
- Difficulty thinking, concentrating, or making decisions.
- Slowed thinking or movement (psychomotor retardation).
Behavioural Symptoms:
- Agitation or restlessness.
- Withdrawal from social activities or relationships.


Diagnosis of Depression in the UK
Depression is diagnosed based on:
- The presence of symptoms for at least two weeks.
- The severity of symptoms and their impact on daily functioning.
- Ruling out other medical conditions or substance use that may mimic depressive symptoms.
Treatment Options Based on NICE Guidelines
The National Institute for Health and Care Excellence (NICE) provides evidence-based recommendations for treating depression. Treatment options include:
- Cognitive Behavioural Therapy (CBT): First-line treatment for mild to moderate depression. CBT helps individuals identify and change negative thought patterns and behaviours.
- Interpersonal Therapy (IPT): Focuses on improving relationships and communication skills.
- Mindfulness-Based Cognitive Therapy (MBCT): Helps prevent relapse in individuals with recurrent depression.
Selective Serotonin Reuptake Inhibitors (SSRIs): First-line antidepressants (e.g., sertraline, fluoxetine).
Serotonin-Noradrenaline Reuptake Inhibitors (SNRIs): Alternative to SSRIs (e.g., venlafaxine, duloxetine).
Tricyclic Antidepressants (TCAs): Used for severe depression if SSRIs or SNRIs are ineffective.
Medication is tailored to individual needs and monitored for effectiveness and side effects.
- Regular exercise, a balanced diet, and good sleep hygiene.
- Support groups and peer support to reduce feelings of isolation.
- For moderate to severe depression, a combination of psychological therapy and medication is often recommended.
- In cases of severe depression or suicidal thoughts, immediate support may include crisis intervention, hospitalisation, or referral to specialist mental health services.

How New Healing Solutions Clinic (NHSC) Can Help
At New Healing Solutions Clinic (NHSC), we provide expert assessment and evidence-based treatment for depression, following NICE guidelines. Our services include:
Accurate Assessment and Diagnosis:
- Comprehensive evaluation using NHS-recommended screening tools.
- Identification of individual needs and treatment goals.
Personalised Treatment Plans:
- Psychological therapies, medication, and lifestyle recommendations tailored to each individual.
- Regular follow-ups to monitor progress and adjust treatment as needed.
Confidential Care:
- Your privacy is our priority. All consultations are strictly confidential.

Take the First Step Toward Recovery
If you or a loved one is struggling with depression, don’t wait to seek help. Contact New Healing Solutions Clinic (NHSC) today for an expert assessment and personalised treatment plan. Begin your journey to improved mental health and well-being.
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